李娜，女，毕业于北京大学，现任北京大学化学与分子工程学院博士，教授，博士生导师。

1994-1998年，北京大学化学学院工作。

1999-2000年，美国堪萨斯大学药化系CDDR博士后。

2000年，北京大学化学学院工作。

研究领域和兴趣

主要研究方向为光学传感新原理、新方法。

光学传感新原理、新方法。主要兴趣为：基于金属纳米材料光谱（荧光、局域表面等离子体共振吸收/散射）的生物传感，以及生物大分子与小分子的相互作用。

具有纳米层间结构固定相的合成、酶及其他分子的固定化及其应用于分离以及光学传感器的研究等。生物大分子（蛋白质，核酸，糖类物质等）与小分子的超分子作用及其在生物大分子测定方面的应用研究。

口腔保健产品临床功能的实验室评价方法的建立及实施，如牙膏和洁牙剂的摩擦力及物理和化学清洁力的国际标准的建立和评价，与龋病病相关的牙釉质脱矿和再矿化程度的定量测定方法的建立等。临床数据的统计处理。

著作

论文

1. Tian Li, Xi Wu, Guangyu Tao, Haoyan Yin, Junlong Zhang, Feng Liu,Na Li*

A simple and non-amplification platform for femtomolar 脱氧核糖核酸 and microRNA detection by combining automatic gold nanoparticle enumeration with target-induced strand-displacement.

Biosens. Bioelectron. 2018, 105, 137-142.

2. Xiaojing Pei, Tiancheng Lai, Guangyu Tao, Hu Hong, Feng Liu,Na Li*

Ultra-specific multiplexeddetection of low-abundance single-nucleotide variants by combining masking tactic with fluorescent nanoparticle counting.

Anal. Chem.2018,90, 4226-4233.

3. Xiaojing Pei, Haoyan Yin, Tiancheng Lai, Junlong Zhang, Feng Liu, Xiao Xu*,Na Li*

Multiplexed Detection of Attomole Nucleic Acids Using Fluorescent Nanoparticle Counting Platform

Anal. Chem.2018, 90, 1376-1383.

4. Guangyu Tao, Yang Chen, Ruoyun Lin, Jiang Zhou, Xiaojing Pei, Feng Liu,Na Li

How G-quadruplex topology and loop sequences affect optical properties of 脱氧核糖核酸templated 银 nanoclusters

Nano Res.2017, 11,223-2247.

5. Ruoyun Lin, Guangyu Tao, Yang Chen, Mingxing Chen, Feng Liu,Na Li*.

Constructing a robust fluorescent DNA-stabilized silver nanocluster probe module by attaching a duplex moiety

Chem. Eur. J.2017,23, 10893-10900.

6. Runyun Lin, Chenxi Li, Yang Chen, Feng Liu,Na Li*

Metal-enhanced 荧光 in biosensing applications, "surface PLASMON Enhanced, Coupled and Controlled Fluorescence",2017, Edited by Geddes, C. D., Wiley, NJ. (Invited chapter).

7. Wu, Xi, Tian Li, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu,Na Li.

Universal and Enzyme-Free Immunoassay Platform for Biomarker Detection Based on Gold Nanoparticle Enumeration with a Dark-Field 显微镜

Analyst,2017, 142, 4201-4205.

8. Tian Li, Xi Wu, Feng Liu,Na Li*.

Analytical Methods Based on the Light-Scattering of Plasmonic Nanoparticles at the Single Particle Level with Dark-Field Microscopy Imaging.

Analyst,2017, 142, 248-256.

9. Chenxi Li, Yixin Li, Yang Chen, Ruoyun Lin, Tian Li, Feng Liu,Na Li*

Modulating the 脱氧核糖核酸 strand-displacement kinetics with the one-sided remote toehold 设计 for differentiation of single-base mismatched DNA.

RSC Adv. 2016, 6, 74913-74916.

10. Yang Chen, Guangyu Tao, Ruoyun Lin, Xiaojing Pei, Feng Liu, Na Li*

Pre-Incubation of Auric Acid with 脱氧核糖核酸 Is Unnecessary for the Formation of DNA-Templated Gold Nanoclusters

Chem.-an Asian J.2016,11, 1677-1681.

11. Tian Li, Xiao Xu, Guoqing Zhang, Ruoyun Lin, Yang Chen, Chenxi Li, Feng Liu, Na Li*

Nonamplification 三明治 Assay Platform for Sensitive Nucleic Acid Detection Based on Aunps Enumeration with the Dark-Field 显微镜

Anal. Chem. 2016,88, 4188-4191.

12. Xiao Xu, Tian Li, Zhongxing Xu, Hejia Wei, Ruoyun Lin, Bin Xia, Feng Liu, Na Li*

Automatic enumeration of gold nanomaterials at single particle level

Anal. Chem.2015,87, 2576-2581.

13. Hongduan Huang, Hejia Wei, Mingjian Zou, Xiao Xu, Bin Xia*, Feng Liu, Na Li*

Modulating 荧光 anisotropy of terminally labeled dsDNA via the interaction between dye and nucleotides for rational 设计 of 脱氧核糖核酸recognition based applications

Anal. Chem.2015, 87, 2748-2754.

14. Zhenpeng Zhou, Tian Li, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,*Na Li*

A dual amplification strategy for DNA detection combining bio-barcode assay and metal-enhanced 荧光 modality.

Chem. Commun.2014,50, 13373-13376.

15. Chenxi Li, Yixin Li, Xiao Xu, Xinyi Wang, Yang Chen, Xiaoda Yang, Feng Liu, Na Li*

Fast and quantitative differentiation of single-base mismatched 脱氧核糖核酸 by initial reaction rate of 催化 hairpin assembly.

Biosens. Bioelectron.2014,60,57-63.

16. Zhenpeng Zhou, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang, Na Li*

A distance-dependent metal-enhanced 荧光 sensing Platform based on molecular beacon 设计

Biosens. Bioelectron. 2014, 52, 367-373.

17. Xinyi Wang, Mingjian Zou, Hongduan Huang, Yuqian Ren, Limei Li, Xiaoda Yang, Na Li*

Gold nanoparticle enhanced 荧光 anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction

Biosens. Bioelectron.2013,41, 569-575.

18. Xiao Xu, Yang Chen, Hejia Wei, Bin Xia, Feng Liu, Na Li*

Counting Bacteria Using Functionalized Gold Nanoparticles as the Light-Scattering Reporter

Anal. Chem.2012,84, 9721-9728.

19. Mingjian Zou, Yang Chen, Xiao Xu, Hongduan Huang, Feng Liu,Na Li*

The homogeneous 荧光 Anisotropic Sensing of Salivary Lysozyme Using the 6-carboxy fluorescein-labeled 脱氧核糖核酸 Aptamer.

Biosens. Bioelectron.2012,32, 148-154.

从1994年参加分析化学实验、仪器分析实验、高等分析实验教学，以及定量化学分析课教学。现主讲定量化学分析。