惠永正(1939年12月-2020年12月22),男,江苏苏州人,1962年毕业于
北京大学化学系。后就职于中科院上海有机化学研究所、国家科委等。
惠永正同志,因病于2020年12月22日在上海逝世,享年82岁。
人物经历
1959.9-1962.7 北京大学
1962.9- 中科院上海有机化学研究所
1982.2-1983.1 美国 University of North Carolina at Chapel Hill
1983.2-1983 12 美国 Rutgers University
1991.1- 国家科委
1998年至2000年,任科学技术部副部长。
2020年12月22日,因病在上海逝世,享年82岁 。
人物逝世
中国共产党的亲密朋友,无党派人士的优秀代表,我国科技战线的优秀领导者,第七届全国政协委员,第八届、九届全国人大代表,科学技术部原副部长惠永正同志,因病于2020年12月22日在上海逝世,享年82岁。
主要工作成就
惠永正早期从事物理有机
化学研究,系统地研究了糖淀粉及其衍生物作为宿主体系的宿主-客体化学,随后研究领域扩展到
计算机化学和微泡体化学。近年来主要从事微泡体化学和糖化学研究,包括长链、多代长链化物的微泡体的性质和生物合功能模拟: 复杂
低聚糖的化学合成及
糖缀合物中糖链与生物功能之间关系的研究。早年曾从事计算机化学和微环境效应研究,曾获
全国科学大会奖(1978),中科院科学进步
一等奖(1986),国家自然科学
三等奖(1988),和中科院发明一等奖(1997)。至今共发表论文71篇。共培养硕士研究生7,博士研究生6名,合作培养博士生8名。
发表论文
1. Inter-Domain Movenment of Spin Lables in the Vesicle Monolayers of Hybride bolaamphiphiles.
B.Y.Z.Hui, Supramolecular Chem., 1995, 5, 193-195
2. Direct Facile Tetrahydrofuranylation of Alcohols in p-TsCl/
氢化钠/THF System.
B.Y.Z.Hui, Synth. Commun., 1995, 25, 2037
3. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of -Acyl-D-glucopyranosides.
J.Xia, Y.Z.Hui, Synth. Commun., 1995, 25, 2235-2251
4. An Efficient and Stereospecific Synthesis of 1-Stearoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophosphocholine and its Bioactivity.
J.Xia, Y.Z.Hui, Bioorg. Med. Chem. Lett., 1995, 5(17),1919-1922
5. A New Strategy for the Stereoselective Synthesis of 2,3-Dideoxy-3-Fluoro-D-Ribofuranose Derivatives.
Z.W.Guo, B.G.Huang, W.J.Xia, Y.Z.Hui, S..Lang, Chin. J. Chem., 1995, 13,363
6. Chemical Synthesis of a Commonly Occurring
皂苷 Trisaccharide: a -L-Rhaminosyl-(1-4)-b nosyl-(1-6)-D-Glucopyranose.
MZLiu, Z.W.Guo, Y.Z.Hui, Carbonhydr. Lett., 1995, 1, 387-392
7. An Efficient and Stereospecific Synthesis of 1-Palmitoyl-2-[(z,z,z)-9,12,15-Linolenoyl]-sn-Glycerophophocholine.
J.Xia, Y.Z.Hui, Chin. Chem. Lett., 1995, 6(10), 863-866
8. A General Method for the Synthese of Ether Phospholipids with a -Linolenic Acid and Their Properties.
J.Xia, Y.Z.Hui, Bioorg. Med. Chem. Lett., 1995, 5(23), 2815-2820
9. A New Highly Regioselective Reaction of Unprotected Sugars for Chemical Synthesis of Methyl-6-D-Acyl-D-Glycopyranoside by Means of Chlorophosphoric Acid Diethyl Ester as Condensing Reagent.
J.Xia, Y.Z.Hui, Synth. Commun, 1996, 26(2), 269-278
10. A Convenient Method for Highly Selective Deprotection of Benzylidene Acetals from Sugars
J.Xia, Y.Hui, Synth. Commum., 1996, 26(5), 881-886
11. The TMSOTf-Promoted "One Pot" -Glycosidations of Peracetylated Chitobiose.
B.Q. Ouyang, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(3), 297-302
12. Chemical Synthesis of (3-SO3Na) GlcNAc b 1-3Fuc b 1-OMe: The Oligocaccharide Involved in the
细胞 Aggregation of the Sponge Microcina Prolifera.
Z.W.Guo, S.J.Deng, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(8), 965-974
13. A New Strategy for the Stereoselective Syntheses of C-Glycosyl Compounds of b -Pentapyranoses.
Z.W.Guo, Y.Z.Hui, Synth. Commun., 1996, 26(11), 2067-2073
14. Supramolecular Assemblies from Single-Chain Hydrocarbon Fluorocarbon Hybrid Bolaamphiphiles.
B. Y.Z.Hui, Chin. J. Chem., 1996, 14(2), 171-179
15. Structural Study on a Bioactive Fructan from the Root of Achyranthes Bidentata Blume.
B. G.Y.Tian, Y.Z.Hui, Chin. J. Chem., 1996, 13(6), 539-544
16. A One-Step Procedure for Facile, Selective Synthesis of Protected D-Glucopyranosides with Free 2-C Hydroxyl Group Starting from Peracetylated b-D-Glucopyranose.
; M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui, Chin. J. Chem., 1996, 14(2), 190-192
17. One-Step Glycosylation and Selective Deprotection of Peracetylated Monosaccharides for Facile Syntheses of Allyl Glycosides with a Free C-2 Hydroxyl Group.
MZLiu, H.N.Fan, Z.W.Guo, Y.Z.Hui, Carbonhydr. Res., 1996, 290, 233-237
18. A New Reaction for One-pot, Selective Mono-O-Glycosylations of 9,10- Dihydroxyphenanthrene Under Mild Conditions.
Z.W.Guo, Y.Z.Hui, Chin.Chem.Lett., 1996, 7(5), 423-424
19. Isolation and Structure Elucidation of a
多糖 with Radiation-Protective Activity from Spinulina Platensis.
Z.W.Guo, Y.Z.Hui, Chin.J. Chem., 1996, 14(3), 279-285
20. A One-Step Procedure for Facile Preparation of D-Glucopyranosides with a Free 2-OH from Peracetylated b -D-Glucopyranose.
M.Z.Liu, H.N.Fan, Z.W.Guo, Y.Z.Hui, J. Carbohydr. Chem., 1996, 15(9), 1139-1145
21. The Stereospecific Synthesis of Mixed-acid Phospholipids with Polyunsaturated Fatty Acid from D-mannitol.
J. Xia, Y. Z. Hui, Tetrahedron: Asymmetry, 1997, 3, 451-485
22. Recent Progress of
皂苷 Research.
MZLiu, Z.W.Guo, Y.Z.Hui, Natural Product Research and Development, 1997, 9(2), 81-85
23. A Facial Regioselective 1,6-O-Diacetylation Method of
甲基 glycopyranosides and Their Dimethyl Phosphonates.
G.T.Zhang, Z.W.Guo, Y.Z.Hui, Synth. Commun., 1997, 27(11), 1907-1918
24. First Total Synthesis of Tricolorin A.
S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Angew. Chem. Int. Ed. Engl., 1997, 36, 2344-2346.
25. A Synthesis of Tricolorin A.
S., Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui, J.Org.Chem., 1997, 62, 8400-8405.
26. Synthesis and Antitumor Activities of Diosgenyl Glycosides.
MZLiu, , Z.W.Guo, Y.Z.Hui, Carbohydr. Lett., 1997, 2,423-428.
27. Conformational Analysis of Two Diosgenyl Saponins.
M.Z.Liu, , M.B.Chen, C.L.Feng, Y.Z,Hui, Chin. Chem. Lett., 1997, 8, 785-788.
28. A New Method for the
CLEAVAGE of Carbohydrate Benzylidene Acetyl by Ceric (IV) Ammonium Nitrate in CH3
.cnH2O (10:1).
S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Chin. Chem. Lett., 1997, 8, 841.
29. Efficient One-Step
甲基 Esterification of Carboxylic Acid and Deacetylation by BF3OEt2-MeOH.
S., Q.Q.Ouyang, Z.W.Guo, , Y.Z.Hui, Chin. Chem. Lett., 1997, 8, 843.
30. What is the Sugar Chains¡¯
函数 in
皂苷MZLiu, Z.W.Guo, Y.Z.Hui, Youji Huaxue, 1997, 17, 307.
31. Recent Progress on Resin
糖苷 Research.
S., Q.Q.Ouyang, Z.W.Guo, Y.Z.Hui, Youji Huaxue, 1997, 17(4), 1