母义明,男,1962年生,先后毕业于
中国人民解放军海军军医大学、日本国立
九州大学,
医学博士,
主任医师,
中国人民解放军医学院、
清华大学医学院教授,博士生导师,现任中国人民解放军总医院(北京301医院)内分泌科主任。
人物经历
学习经历
1989-1991年解放军军医进修学院医学硕士学位
1997-2001年日本国立九州大学医学部医学博士学位
工作经历
1984-1991 解放军总医院内分泌科住院医师
1994-1996 解放军总医院内分泌科
副主任医师、副教授
主要成就
擅长领域
糖尿病 、甲状腺疾病 、垂体-
肾上腺疾病 、性腺疾病
研究方向
2.遗传因素对儿童青少年糖尿病发生的影响及其机制
3.糖尿病患者围手术期血糖管理
承担课题项目
先后承担国家重大科技研究项目3项和国家自然科学基金5项。
1.自体血
免疫细胞教育新疗法治疗糖尿病
分子生物学机制的研究
2.临床标本资源库
3.干细胞治疗糖尿病的临床前方案优化及临床应用研究
6.2型糖尿病危险因素的动态监测与社区综合防治
8.糖尿病患者围手术期血糖管理规范研究
人才培养
个人作品
发表SCI论文200余篇,国内核心期刊发表论文500余篇。
代表论文
1. Wang Y, Wang A, Ye Y, Gao Z, Tang X, Yan L, Wan Q, Wang W, Luo Z, Qin Q, Chen L and Mu Y. Elevated triglycerides rather than other lipid parameters are associated with increased urinary albumin to
肌酸酐 ratio in the general
种群 of China: a report from the REACTION stud. Cardiovasc Diabetol (2019) 18:57. https://
doiorg/10.1186/ s12933-019-0863-8. (通讯作者)
2. Gu S, Wang A, Ning G, Zhang L and Mu Y. Insulin resistance is associated with urinary albumin-
肌酸酐 ratio in normal weight individuals with hypertension and
糖尿病: the REACTION study. J Diabetes 2019 Nov 26. doi: 10.1111/1753-0407.13010. [Epub ahead of print] (通讯作者)
3. Yu S,
成姓 Y, Zhang L, Yin Y, Xue J, Li B, Gong Z, Gao J and Mu Y. Treatment with adipose tissue-derived mesenchymal stem cells exerts antidiabetic effects, improves long-term complications, and attenuates inflammation in type 2 diabetic
鼠科 Stem Cell Research \u0026 Therapy (2019) 10:333 https://d
oiorg/10.1186/s13287-019-1474-8. (通讯作者)
4. Mao W, Jin X, Wang H, Ye Y, Zhang L, Gu S, Wang J, Ning G, Mu Y. The Association between Resting Heart Rate and Urinary Albumin/
肌酸酐 Ratio in Middle-Aged and Elderly Chinese Population: A Cross-Sectional Study. J
糖尿病 Res. 2019 Aug 25;2019:9718370. doi: 10.1155/2019/9718370. eCollection 2019. (通讯作者)
5. Gao Y, Wang J, Luo X, Song X, Liu L, Ke L, Liao Z, Wang D, Mu Y, Chen Y, Estill JAM.Quality appraisal of clinical practice guidelines for
糖尿病 mellitus published in China between 2007 and 2017 using the AGREE II instrument. BMJ Open. 2019 Sep 4;9(9):e022392. doi: 10.1136/bmjopen-2018-022392.
6. Ye Y, Zhang L, Yan W, Wang A, Wang W, Gao Z, Tang X, Yan L, Wan Q, Luo Z, Qin G, Chen L, Wang S, Wang Y, Mu Y. Self-reported sleep duration and day
时间 napping are associated with renal hyperfiltration and microalbuminuria in an apparently healthy
汉语词类 population. PLoS One. 2019 Aug 30;14(8):e0214776. doi: 10.1371/journal.pone.0214776. eCollection 2019. (通讯作者)
7. Gao J, Cheng Y, Hao H, Yin Y, Xue J, Zhang Q, Li L, Liu J, Xie Z, Yu S, Li B, Han W, Mu Y. Decitabine assists umbilical cord-derived mesenchymal stem cells in improving glucose homeostasis by modulating macrophage polarization in type 2 diabetic
鼠科 Stem Cell Res Ther. 2019 Aug 19;10(1):259. doi: 10.1186/s13287-019-1338-2. (通讯作者)
8. Wang T, Lu J, Su Q, Chen Y, Bi Y, Mu Y, Chen L, Hu R, Tang X, Yu X, Li M, Xu M, Xu Y, Zhao Z, Yan L, Qin G, Wan Q, Chen G, Dai M, Zhang D, Gao Z, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Bloomgarden ZT, Shi L, Ning G, Zhao J, Wang W; 4C Study
基团Ideal Cardiovascular Health Metrics and Major Cardiovascular Events in Patients With Prediabetes and
糖尿病 JAMA Cardiol. 2019 Jul 31. doi: 10.1001/jamacardio.2019.2499. [Epub ahead of print]
9. Wang J, Chen K, Jin X, Li X, An P, Yang N, Chen Y, Fang Y, Mu Y. Prognostic factors for cesarean section outcome of pregnant women with gestational
糖尿病 mellitus: a systematic review and
后设analysis. Diabetes Metab Syndr Obes. 2019 Jun 21;12:913-929. doi: 10.2147/DMSO.S188293. eCollection 2019. (通讯作者)
10. Zang L, Han Y, Chen L, Hu D, Jin H, Yang N, Shi X, Liang L, Liu M, Fan H, Li Q, Mu Y.Comparison of the Effectiveness and Safety of Vildagliptin Add-On to Metformin Versus Other Oral Dual Antidiabetes Agents in Patients with Type 2
糖尿病: The China Prospective Diabetes Study. Diabetes Ther. 2019 Aug;10(4):1391-1405. doi: 10.1007/s13300-019-0645-z. Epub 2019 Jun 20. (通讯作者)
11. Hu C, Mu Y, Wan Q, Qin Y, Hu R, Shi L, Su Q, Yu X, Yan L, Qin G, Tang X, Chen G, Gao Z, Wang G, Shen F, Luo Z, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Liu C, Wang Y, Wu S, Yang T, Deng H, Chen L, Zhao J, Lu J, Lin L, Li M, Du R, Xu M, Xu Y, Wang T, Zhao Z, Chen Y, Li D, Bi Y, Wang W, Ning G; REACTION Study Group. Association between birth weight and
糖尿病: Role of body mass index and lifestyle in later life. J Diabetes. 2019 Jun 6. doi: 10.1111/1753-0407.12960. [Epub ahead of print](并列
第一作者)
12. Lu J, He J, Li M, Tang X, Hu R, Shi L, Su Q, Peng K, Xu M, Xu Y, Chen Y, Yu X, Yan L, Wang T, Zhao Z, Qin G, Wan Q, Chen G, Dai M, Zhang D, Gao Z, Wang G, Shen F, Luo Z, Qin Y, Chen L, Huo Y, Li Q, Ye Z, Zhang Y, Du R,
成姓 D, Liu C, Wang Y, Wu S, Yang T, Deng H, Li D, Lai S, Bloomgarden ZT, Chen L, Zhao J, Mu Y, Ning G, Wang W, Bi Y; 4C Study Group. Predictive Value of Fasting Glucose, Postload Glucose, and Hemoglobin A1c on Risk of Diabetes and Complications in
汉语词类 Adults.
糖尿病 Care. 2019 Aug;42(8):1539-1548. doi: 10.2337/dc18-1390. Epub 2019 May 31.
13. Gu Y, Gu W, Dou J, Lu Z, Ba J, Li J, Wang X, Liu H, Yang G, Guo Q, Zang L, Chen K, Du J, Pei Y, Mu Y. Diagnostic Role of Prostate-Specific Membrane
抗原 in Adrenocortical Carcinoma. Front Endocrinol (
洛桑). 2019 Apr 16;10:226. doi: 10.3389/fendo.2019.00226. (通讯作者)
14. Wang J, Li Y, Chen K, Yan W, Wang A, Wang W, Gao Z, Tang X, Yan L, Wan Q, Luo Z, Qin G, Chen L, Mu Y. Association between Duration of Exercise (MET Hours per Week) and the Risk of Decreased eGFR: A Cross-Sectional Study Based on a Large Chinese Population. J
糖尿病 Res. 2019 Mar 21;2019:5874603. doi: 10.1155/2019/5874603. eCollection 2019. (通讯作者)
15. Wang J, Chen K, Li X, Jin X, An P, Fang Y, Mu Y. Postoperative adverse events in patients with diabetes undergoing orthopedic and general surgery.
药品 (Baltimore). 2019 Apr;98(14):e15089. doi: 10.1097/MD.0000000000015089. (通讯作者)
16. Jiang J, Cui J, Wang A, Mu Y, Yan Y, Liu F, Pan Y, Li D, Li W, Liu G, Gaisano HY, Dou J, He Y. Association Between Age at Natural Menopause and Risk of Type 2
糖尿病 in Postmenopausal Women With and Without Obesity. J Clin Endocrinol Metab. 2019 Jul 1;104(7):3039-3048. doi: 10.1210/jc.2018-02310.
17. Wang J, Pei Y, Chen K, Yan W, Wang A, Li Y, Li J, Wang H, An P, Zhang L, Ye Y, Jin X, Ning G, Mu Y, Gu W. Association between the Number of Childbirths and the Progress of Atherosclerosis among Women with
糖尿病: A Cohort Study Based on Chinese Population. Int J Endocrinol. 2019 Jan 27;2019:4874121. doi: 10.1155/2019/4874121. eCollection 2019. (通讯作者)
18. Zhao L, Pang P, Zang L, Luo Y, Wang F, Yang G, Du J, Wang X, Lyu Z, Dou J, Mu Y. Features and trends of thyroid cancer in patients with thyroidectomies in Beijing, China between 1994 and 2015: a retrospective study. BMJ Open. 2019 Jan 25;9(1):e023334. doi: 10.1136/bmjopen-2018-023334.
19. Li J, Li T, Wang H, Yan W, Mu Y. Neutrophil-
淋巴细胞 ratio as a predictor of
肾脏 function decline among individuals with
糖尿病 and prediabetes: A 3-year follow-up study. J Diabetes. 2019 Jun;11(6):427-430. doi: 10.1111/1753-0407.12903. Epub 2019 Feb 11. No abstract available. (通讯作者)
20. Liu M, Li X, Ha S, Wang A, Yin S, Mu Y. Angiotensin Type 2 Receptor Agonist C21 Ameliorates the High-Fat Diet-Induced Pancreatic β-
细胞 Dysfunction Partially by Activation of Antiapoptosis and Autophagy. Pancreas. 2019 Feb;48(2):250-256. doi: 10.1097/MPA.0000000000001241.
21. Zhao L, Yan H, Pang P, Fan X, Jia X, Zang L, Luo Y, Wang F, Yang G, Gu W, Du J, Wang X, Lyu Z, Dou J, Mu Y. Thyroid nodule size calculated using ultrasound and gross
病理学 as predictors of cancer: A 23-year retrospective study.Diagn Cytopathol. 2019 Mar;47(3):187-193. doi: 10.1002/dc.24068. Epub 2018 Nov 29.
22. Song X, Wang J, Gao Y, Yu Y, Zhang J, Wang Q, Ma X, Estille J, Jin X, Chen Y, Mu Y. Critical appraisal and systematic review of guidelines for perioperative
糖尿病 management: 2011-2017. Endocrine. 2019 Feb;63(2):204-212. doi: 10.1007/s12020-018-1786-y. Epub 2018 Nov 16. Review. (通讯作者)
23. Pan G, Mu Y, Hou L, Liu J. Examining the therapeutic potential of various stem cell sources for differentiation into
胰岛素producing cells to treat
糖尿病 Ann Endocrinol (Paris). 2019 Feb;80(1):47-53. doi: 10.1016/j.ando.2018.06.1084. Epub 2018 Jul 2
24. Zhou X, Gong Y, Tian J, Yang G, Li F, Li L, Ba J, Dou J, Mu Y. Retrospective clinical analysis of glucose
新陈代谢 in
肢端肥大症 patients. Minerva Endocrinol. 2019 Jun;44(2):233-235. doi: 10.23736/S0391-1977.18.02772-4. Epub 2018 Jul 23. No abstract available.
25. Yulong Chen. Quanmin Li. Ying Han. Hongmei Ji. Mingjun Gu. Rongwen Bian. Weiguang Ding. Jian
成姓Yiming M. Vildagliptin Versus a-Glucosidase Inhibitor as
插件 to Metformin for Type 2
糖尿病: Subgroup Analysis of the China Prospective Diabetes Study. Diabetes Ther 2019 https://
doiorg/10.1007/s13300-019-00742-8(通讯作者)
26. Gu Y, Gu W, Dou J, Lv Z, Li J, Zhang S, Yang G, Guo Q, Ba J, Zang L, Jin N, Du J, Pei Y, Mu Y. Bilateral adrenocortical adenomas causing adrenocorticotropic hormone-independent Cushing’s
综合征: A case report and review of the literatur. World J Clin Cases 2019 April 26; 7(8): 961-971.
27. Liu J, Zhu D, Mu Y, Xia W.
管理学 of
断裂 risk in patients with
糖尿病—
汉语词类 Expert Consensus. Journal of Diabetes. 2019;1–14.
28. Zang L, Hong Q, Yang G, Gu W, Wang A, Dou J, Mu Y, Wu D, Lyu Z. MACROD1/LRP16 Enhances LPS-Stimulated Inflammatory Responses by Up-Regulating a Rac1-Dependent Pathway in Adipocytes.
细胞 Physiol Biochem. 2018;51(6):2591-2603. doi: 10.1159/000495931. Epub 2018 Dec
29. Lu J, Wang W, Li M, Bi Y, Xu Y, Chen L, Zhao J, Mu Y, DeFronzo RA, Ning G. Associations of Hemoglobin A1c With Cardiovascular Disease and Mortality in Chinese Adults With
糖尿病 J Am Coll Cardiol. 2018 Dec 18;72(24):3224-3225. doi: 10.1016/j.jacc.2018.09.062.
30. Yin Y, Hao H, Cheng Y, Zang L, Liu J, Gao J, Xue J, Xie Z, Zhang Q, Han W, Mu Y. Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic
鼠科 Cell Death Dis. 2018 Jul 9;9(7):760. doi: 10.1038/s41419-018-0801-9. (通讯作者)
31. Gu W, Gu Y, Li J, Yang G, Guo Q, Zang L, Du J, Pei Y, Ba J, Lv Z, Dou J, Mu Y. A Craniopharyngioma Associated With Elevated Cerebrospinal Fluid HCG Concentrations Misdiagnosed as a Germinoma. Front Neurol. 2018 Jun 14;9:449. doi: 10.3389/fneur.2018.00449. eCollection 2018. (共同通讯作者)
32. Yin Y, Hao H,
成姓 Y, Gao J, Liu J, Xie Z, Zhang Q, Zang L, Han W, Mu Y. The homing of human umbilical cord-derived mesenchymal stem cells and the subsequent modulation of macrophage polarization in type 2 diabetic mice. Int Immunopharmacol. 2018 Jul;60:235-245. doi: 10.1016/j.intimp.2018.04.051. Epub 2018 May 25. (共同通讯作者)
33. Yin Y, Ye S, Wang H, Li B, Wang A, Yan W, Dou J, Mu Y.
红色 blood
细胞 distribution width and the risk of being in poor glycemic
监察 among patients with established type 2
糖尿病 Ther Clin Risk Manag. 2018 Feb 14;14:265-273. doi: 10.2147/TCRM.S155753. eCollection 2018. (通讯作者)
34. Wang G, Liu H, Wang C, Ji X, Gu W, Mu Y. Cinacalcet versus Placebo for secondary hyperparathyroidism in chronic
肾脏 disease patients: a
后设analysis of randomized controlled trials and trial sequential analysis.Sci Rep. 2018 Feb 15;8(1):3111. doi: 10.1038/s41598-
01821397-8. (通讯作者)
35. Weng J, Zhou Z, Guo L, Zhu D, Ji L, Luo X, Mu Y, Jia W; T1D China Study
基团 Incidence of type 1
糖尿病 in China, 2010-13:
种群 based study. BMJ. 2018 Jan 3;360:j5295. doi: 10.1136/bmj.j5295.
36. Peng K, Chen G, Liu C, Mu Y, Ye Z, Shi L, Zhao J, Chen L, Li Q, Yang T, Yan L, Wan Q, Wu S, Wang G, Luo Z, Tang X, Huo Y, Gao Z, Su Q, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Xu Y, Xu M, Chen Y, Lu J, Lin L, Du R, Dai M, Li M, Wang T, Zhao Z, Zhang D, Bi Y, Li D, Wang W, Ning G; REACTION Study Group. Association between smoking and glycemic control in diabetic patients: Results from the Risk Evaluation of cAncers in Chinese diabeTic Individuals: A lONgitudinal (REACTION) study. J
糖尿病 2018 May;10(5):408-418. doi: 10.1111/1753-0407.12625. Epub 2018 Jan 18.
37. Chen K, Kang D, Yu M, Zhang R, Zhang Y, Chen G, Mu Y. Direct head-to-head comparison of glycaemic durability of dipeptidyl peptidase-4 inhibitors and sulphonylureas in patients with type 2
糖尿病 mellitus: A
后设analysis of long-term randomized controlled trials. Diabetes Obes Metab. 2018 Apr;20(4):1029-1033. doi: 10.1111/dom.13147. Epub 2017 Dec 5. (通讯作者)
38. Li L, Yang G, Dou J, Gu W, Lv Z, Lu J, Mu Y. The Role of Cortisol/ACTH Ratio for Screening of Subclinical Hypercortisolism in Patients with Adrenal Incidentalomas.Exp Clin Endocrinol
糖尿病 2018 Feb;126(2):71-76. doi: 10.1055/s-0043-101236. Epub 2017 Sep 20.
39. Mu Y, Liu X, Li Q, Chen K, Liu Y, Lv X, Xu X, Fan D, Shang N, Yang R, Pauer L, Pan C. Efficacy and safety of pregabalin for painful diabetic peripheral neuropathy in a
种群 of Chinese patients: A randomized placebo-controlled trial. J Diabetes. 2018 Mar;10(3):256-265. doi: 10.1111/1753-0407.12585. Epub 2017 Nov 1.(
第一作者)
40. Zhao K ,Yang S, Wang H,Chen K,Zhao H , Mu Y. Association between the Hypertriglyceridemic Waist Phenotype and Prediabetes in Chinese Adults Aged 40 Years and Older. Journal of
糖尿病 Research Volume 2018, Article ID 1031939, 9 pages https://
doiorg/10.1155/2018/1031939 (通讯作者)
41. Du J, Liang L, Fang H, Xu F, Li W, Shen L, Wang X, Xu C, Bian F, Mu Y. Efficacy and safety of saxagliptin compared with acarbose in Chinese patients with type 2
糖尿病 mellitus uncontrolled on metformin monotherapy: Results of a Phase IV open-label randomized controlled study (the SMART study).Diabetes Obes Metab. 2017 Nov;19(11):1513-1520. doi: 10.1111/dom.12942. (通讯作者)
42. Gu W, Liu Y, Liu H, Yang G, Guo Q, Du J, Jin N, Zang L, Lv Z, Ba J, Mu Y* and Dou J*.Characteristics of glucose
新陈代谢 indexes and continuous glucose monitoring system (CGMS) in patients with insulinoma. Diabetol Metab Syndr (2017) 9:17.DOI 10.1186/s13098-017-0215-3.(共同通讯作者)
43. Zang L†, Hao H†, Liu J, Li Y, Han W and Mu Y*. Mesenchymal stem cell therapy in type 2
糖尿病 mellitus. Diabetol Metab Syndr (2017) 9:36.DOI 10.1186/s13098-017-0233-1. (通讯作者)
44. Gao F. , Zang L. , Wu D., Li Y.J, Zhang Q., Wang H.B., Tian G.L., Mu Y.M. Pioglitazone improves the ability of learning and memory via activating ERK1/2 signaling
神经通路 in the hippocampus of
2型糖尿病 家鼠属 Neuroscience Letters 651 (2017) 165–170. (通讯作者)
45. Yu Cheng†, Jing Shen†, Weizheng Ren, Haojie Hao, Zongyan Xie,
赵礼杰 Liu, Yiming Mu*, Weidong Han*.Mild
高血糖 triggered islet function recovery in streptozotocin-induced insulin-deficient diabetic
家鼠属 J
糖尿病 Investig 2017; 8: 44–55. (通讯作者)
46. Qing-Hua Guo #,
成姓Zhi Wang # , Zhi-Qiang Wu, Yan Qin,
白姓Yu Han,An-Ping Wang , Bao-An Wang, Jing-Tao Dou, Xiao-Sheng Wu, *, Yi-Ming Mu, *Multi-genic pattern found in rare type of hypopituitarism: a whole-exome sequencing study of Han
汉语词类 with pituitary stalk interruption syndrome. J. Cell.
摩尔 Med. Vol XX, No X, 2017 pp. 1-7. (通讯作者)
47. Chen K, Kang D, Yu M, Zhang R, Zhang Y, Chen G, Mu Y. Direct head-to-head comparison of glycemic durability of dipeptidyl peptidase-4 inhibitors and sulphonylureas in patients with type 2
糖尿病 mellitus: a
后设analysis of long-term randomized controlled trials. Diabetes Obes Metab. 2017 Nov 2. doi: 10.1111/dom.13147. (通讯作者)
48. Wei-Jun Gu, Qian Zhan, Jian Zhu, Jie Li, Shi-Hui Wei, Yi-Ming Mu.∗
利妥昔单抗注射液 was used to treat recurrent IgG4-related hypophysitis with ophthalmopathy as the initial presentation A case report and literature review.Medicine (2017) 96:24. (通讯作者)
49. Gu W. Liu Y. Chen Y. Deng W. Ran X. Chen L. Zhu D. Yang J. Shin J. Lee SW, Cordero TL, Mu Y*. Multicentre randomized controlled trial with sensor-augmented pump vs multiple daily injections in hospitalized patients with type 2
糖尿病 in China: Time to reach target glucose.Diabetes \u0026
新陈代谢 43 (2017) 359–363. (通讯作者)
50. Xiaoya Sun, Haojie Hao, Qingwang Han, Xiaoyan Song, Jiejie Liu, Liang Dong, Weidong Han* ,Yiming Mu*.Human umbilical cord-derived mesenchymal stem cells ameliorate
胰岛素 resistance by suppressing NLRP3 inflammasome-mediated inflammation in type 2
糖尿病 家鼠属 Stem Cell Research \u0026 Therapy (2017) 8:241. (通讯作者)
51. Yiming Mu, Changyu Pan*, Bei Fan, Uwe Hehnke, Xiuzhen Zhang, Xuejun Zhang, Xiaoyue Wang, Jingdong Liu, Ying Zhang, Jianling Du,Jianhua Ma, Yan Gong. Efficacy and safety of linagliptin/metformin single-pill combination as initial therapy in drug-naı¨ve Asian patients with type 2
糖尿病 Diabetes Research and Clinical Practice.124(2017):48-56. (
第一作者)
52. Wang A, Li T, An P, Yan W, Zheng H, Wang B, Mu Y. Exendin-4 Upregulates Adiponectin Level in Adipocytes via Sirt1/Foxo-1 Signaling
神经通路 PLoS ONE. 2017 Jan 25;12(1):e0169469.(通讯作者)
53. Zhang Q, Hao H, Xie Z,
成姓 Y, Yin Y, Xie M, Huang H, Gao J, Liu H, Tong C, Zang L, Mu Y, Han W. M2 macrophages infusion ameliorates obesity and insulin resistance by remodeling inflammatory/macrophages' homeostasis in obese
鼠科 Mol Cell Endocrinol. 2017 Mar 5;443:63-71. (共同通讯作者)
54. Xie M, Hao HJ, Cheng Y, Xie ZY, Yin YQ, Zhang Q, Gao JQ, Liu HY, Mu YM, Han WD. Adipose-derived mesenchymal stem cells ameliorate hyperglycemia through regulating hepatic glucose
新陈代谢 in type 2 diabetic
家鼠属 Biochem Biophys Res Commun. 2017 Jan 29;483(1):435-441. (共同通讯作者)
55. Cheng Y, Shen J, Ren W, Hao H, Xie Z, Liu J, Mu Y, Han W. Mild
高血糖 triggered islet
函数 recovery in STZ-induced insulin-deficient diabetic
家鼠属 J
糖尿病 Investig. 2017 Jan;8(1):44-55. (共同通讯作者)
56. Sun Q, Zheng Y, Chen K, Yan W, Lu J, Dou J, Lv Z, Wang B, Gu W, Ba J, Mu Y.Osteopenia is associated with glycemic levels and blood
压强 in Chinese postmenopausal women: a cross-sectional study.Clin Exp Med. 2017 Feb;17(1):85-91. (共同通讯作者)
57. Wang HB, Yan WH, Dou JT, Lu ZH, Wang BA, Mu YM.Association between Self-reported Snoring and Prediabetes among Adults Aged 40 Years and Older without
糖尿病Chin Med J (Engl). 2017 Apr 5;130(7):791-797. (通讯作者)
58. Xu W, Mu Y, Zhao J, Zhu D, Ji Q, Zhou Z, Yao B, Mao A, Engel SS, Zhao B, Bi Y, Zeng L, Ran X, Lu J, Ji L, Yang W, Jia W, Weng J.Efficacy and safety of metformin and sitagliptin based triple antihyperglycemic therapy (STRATEGY): a multicenter, randomized, controlled, non-inferiority clinical trial.Sci China Life Sci. 2017 Mar;60(3):225-238. (共同第一和通讯作者)
59. Wang CZ, Guo LL, Han BY, Su X, Guo QH, Mu YM.Pituitary Stalk Interruption
综合征: From Clinical Findings to Pathogenesis. J Neuroendocrinol. 2017 Jan;29(1). doi: 10.1111/jne.12451. Review. (通讯作者)
60. Guan X, Mu Y, Zhou X, Chen S, Dong J, Liao L. Efficacy and Safety of
胰岛素 Therapy in Patients with Type 2
糖尿病 Treated at Different Grades of Hospitals in China: Subgroup Analysis of the Real-World SEAS Study. Diabetes Technol Ther. 2017 Jan;19(1):34-40.
61. Meng Q, Ge S, Yan W, Li R, Dou J, Wang H, Wang B, Ma Q, Zhou Y, Song M, Yu X, Wang H, Yang X, Liu F, Alzain MA, Yan Y, Zhang L, Wu L, Zhao F, He Y, Guo X, Chen F, Xu W, Garcia M, Menon D, Wang Y, Mu Y, Wang W. Screening for potential serum-based proteomic biomarkers for human type 2
糖尿病 mellitus using MALDI-TOF MS.
蛋白质组学 Clin Appl. 2017 Mar;11(3-4).
62. Yan HX, Pang P, Wang FL, Tian W, Luo YK, Huang W, Yang GQ, Jin N, Zang L, Du J, Ba JM, Dou JT, Mu YM, Lyu ZH.Dynamic profile of differentiated thyroid cancer in male and female patients with thyroidectomy during 2000-2013 in China: a retrospective study. Sci Rep. 2017 Nov 20;7(1):15832.
63. Yu F, Wei R, Yang J, Liu J, Yang K, Wang H, Mu Y, Hong T. FoxO1
性抑制 promotes differentiation of human embryonic stem cells into
胰岛素 producing cells.Exp
细胞 Res. 2017 Nov 20. pii: S0014-4827(17)30625-0. doi:10.1016/j.yex
铬2017.11.022.
64. Mu YM, Guo LX, Li L, Li YM, Xu XJ, Li QM, Xu MT, Zhu LY, Yuan GY, Liu Y, Xu C, Wang ZJ, Shen FX, Luo Y, Liu JY, Li QF, Wang WH, Lai XY, Xu HF, Pan CY. The efficacy and safety of
胰岛素 degludec versus insulin glargine in insulin-naive subjects with type 2
糖尿病: results of a Chinese cohort from a multinational randomized controlled trial. Zhonghua Nei Ke Za Zhi. 2017 Sep 1;56(9):660-666.(
第一作者)
65. Wei Q, Zang L, Li YJ, Gu WJ, Jin N, Guo QH, Du J, Ba JM, Lyu ZH, Lu JM, Dou JT, Mu YM, Yang GQ. An analysis of four cases of misdiagnosed primary lymphocytic hypophysitis. Zhonghua Nei Ke Za Zhi. 2017 Jul 1;56(7):512-515.
66. Zang L, Liu Y, Geng J, Luo Y, Bian F, Lv X, Yang J, Liu J, Peng Y, Li Y, Sun Y, Bosch-Traberg H, Mu Y.Efficacy and safety of liraglutide versus sitagliptin, both in combination with metformin, in Chinese patients with type 2
糖尿病: a 26-week, open-label, randomised, active comparator clinical trial.Diabetes Obes Metab. 2016 Apr 7. doi: 10.1111/dom.12674. [Epub ahead of print](通讯作者,IF=6.198))
67. Sun W, Shi L, Ye Z, Mu Y, Liu C, Zhao J, Chen L, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Sun J, Ding L, Xu Y, Xu M, Dai M, Wang T, Zhang D, Lu J, Bi Y, Lai S, Li D, Wang W, Ning G; REACTION Study Group.Association between the change in body mass index from early adulthood to midlife and subsequent type 2
糖尿病 mellitus.
肥胖症 (Silver Spring). 2016 Mar;24(3):703-9. doi: 10.1002/oby.21336. Epub 2016 Feb 2.
68. Lu J, Mu Y, Su Q, Shi L, Liu C, Zhao J, Chen L, Li Q, Yang T, Yan L,
万姓 Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Sun J, Sun W, Wang T, Du R, Lin L, Dai M, Xu Y, Xu M, Bi Y, Lai S, Li D, Wang W, Ning G; REACTION Study Group.Reduced
肾脏 Function Is Associated With Cardiometabolic Risk Factors, Prevalent and Predicted Risk of Cardiovascular Disease in
汉语词类 Adults: Results From the REACTION Study.J Am Heart Assoc. 2016 Jul 22;5(7). pii: e003328. doi: 10.1161/JAHA.116.003328. (共同第一作者)
69. Sun J, Lu J, Wang W, Mu Y, Zhao J, Liu C, Chen L, Shi L, Li Q, Yang T, Yan L, Wan Q, Wu S, Liu Y, Wang G, Luo Z, Tang X, Chen G, Huo Y, Gao Z, Su Q, Ye Z, Wang Y, Qin G, Deng H, Yu X, Shen F, Chen L, Zhao L, Bi Y, Xu M, Xu Y, Dai M, Wang T, Zhang D, Lai S, Ning G; REACTION Study
基团Prevalence of
糖尿病 and Cardiometabolic Disorders in Spouses of Diabetic Individuals. Am J Epidemiol. 2016 Sep 1;184(5):400-9. doi: 10.1093/aje/kwv330. Epub 2016 Aug 16.
70. Xie Z, Hao H, Tong C, Cheng Y, Liu J, Pang Y, Si Y, Guo Y, Zang L, Mu Y, Han W.Human umbilical cord-derived mesenchymal stem cells elicit macrophages into an anti-inflammatory phenotype to alleviate
胰岛素 厚膜电阻 in type 2 diabetic
家鼠属Stem Cells. 2016 Mar;34(3):627-39.共同通讯作者,IF=5.902)
71. Zhao K, Hao H, Liu J, Tong C, Cheng Y, Xie Z, Zang L, Mu Y, Han W.Bone marrow-derived mesenchymal stem cells ameliorate chronic high glucose-induced β-cell injury through modulation of autophagy. Cell
死亡 and Disease (2015) 6, e1885; doi:10.1038/cddis.2015.(共同通讯作者,IF=5.378)
72. Cheng Y, Kang H, Shen J, Hao H, Liu J, Guo Y, Mu Y, Han W.Beta-cell regeneration from vimentin+/MafB+ cells after STZ-induced extreme beta-cell ablation. Scientific Reports 07/2015; 5:11703.(共同通讯作者,IF=5.228)
73. Song X, Jia H, Jiang Y, Wang L, Zhang Y, Mu Y, Liu Y. Anti-atherosclerotic effects of the
胰高血糖素like
多肽1 (GLP-1) based therapies in patients with type 2
糖尿病 Mellitus: A metaanalysis. Scientific Reports 2015 Jun 26;5:10202. (共同通讯作者,IF=5.578)
74. Liu J, Liu Y, Wang H, Hao H, Han Q, Shen J, Shi J, Li C, Mu Y, Han W. Direct differentiation of hepatic stem-like WB cells into
胰岛素producing cells using small molecules. Scientific Reports. 2013;3:1185. (共同通讯作者,IF=5.078)
75. Shen J, Cheng Y, Han Q, Mu Y, Han W.Generating insulin-producing cells for diabetic therapy: existing strategies and new development. Ageing Res Rev. 2013 Mar;12(2):469-78.(共同通讯作者,IF=7.628)
76. Type 1
糖尿病 caused by interferon alpha-2alpha in polycythemia vera therapy. Diabetes Care. 2010 Nov;33(11):e141. (SCI收录,IF:7.851)(通讯作者)
77. Yu H, Xie LF, Chen K, Yang GY, Xing XY, Zhao JJ, Hong TP, Shan ZY, Li HM, Chen B, Tang XL, Qi L, Yang J, Fang Y, Li T, Wang SS, Liang X, Yin YQ, Mu YM. Initiating Characteristics of Early-onset Type 2
糖尿病 Mellitus in
汉语词类 Patients. Chin Med J (Engl). 2016 5th Apr;129(7):778-784(通讯作者,IF=1.053)
78. Yang G, Dou J, Zhang X, Gu W, Lv Z, DU J, Ba J, Mu Y, Lu J. Increased 3b-hydroxysteroid dehydrogenase 2 and 17a-hydroxylase activities in a virilized adolescent female with adrenal adenoma: A case report. Exp Ther Med. 2016 Feb;11(2):530-534.(通讯作者,IF=1.269)
79. Sun Q, Zheng Y, Chen K, Yan W, Lu J, Dou J, Lv Z, Wang B, Gu W, Ba J, Mu Y. Osteopenia is associated with glycemic levels and blood pressure in Chinese postmenopausal women: a cross-sectional study. Clin Exp Med. 2015 Nov 29. [Epub ahead of print](通讯作者,IF=2.959)
80. Li Y, Mu Y, Ji Q, Huang Q, Kuang H, Ji L, Yang X.Hypoglycaemia, Abnormal Lipids, and Cardiovascular Disease among Chinese with Type 2
糖尿病 Biomed Res Int. 2015;2015:862896. doi: 10.1155/2015/862896. Epub 2015 Oct 4.(第二作者,IF=2.134)
81. Guo L, Yang G, Gu W, Jin N, Chen K, Du J, Wang X, Ouyang J, Dou J, Ba J, Lv Z, Mu Y. Short-term efficacies of intravenous glucocorticoid therapy for moderate-to-severe Graves' ophthalmopathy. Zhonghua Yi Xue Za Zhi. 2015 May 26;95(20):1572-5.(通讯作者)
82. Li P, Chen K, Nie Y, Guo LL, Wang HB, Wang SS, Wang AP, Hu DY, Mu YM, Li JH; DYSIS-China Study Investigators.Association of
肥胖症 with glucose, blood pressure, and lipid goals attainment in patients with concomitant
糖尿病 and hypertension. Current Medical Research and Opinion.2015,1-9. doi:10.1185/03007995.2015.1058770(通讯作者,IF=2.653)
83. Gu S, Deng J, Shi L, Mu Y, Dong H.Cost-effectiveness of saxagliptin vs
格列美脲 as a second-line therapy added to metformin in Type 2
糖尿病 in China. Journal of Medical Economics, 2015,18:10, 808-820.(第四作者,IF=1.576)
84. Zheng L, Yan W, Kong Y, Liang P, Mu Y. An Epidemiological Study of Risk Factors of Thyroid Nodule and Goiter in Chinese Women. Int. J. Environ. Res. Public Health 2015, 12, 11608-11620; doi:10.3390/ijerph120911608(通讯作者,IF=1.10)
85. Sun QH, Zheng Y, Zhang XL, Mu YM.Role of Gonadotropin-releasing Hormone Stimulation Test in Diagnosing Gonadotropin Deficiency in Both Males and Females with Delayed Puberty. Chin Med J (Engl). 2015 20th Sep;128(18):2439-2443. (通讯作者,IF=1.053)
86. Zhang LX, Gu WJ, Li YJ, Wang Y, Wang WB, Wang AP, Shen L, Zang L, Yang GQ, Lu ZH, Dou JT, Mu YM. PTH Is a Promising Auxiliary Index for the Clinical Diagnosis of Aldosterone-Producing Adenoma. American Journal of Hypertension.Advance Access published August 24, 2015. (通讯作者,IF=2.852)
87. Xie LF, Ouyang JZ, Wang AP, Wang WB, Li XT, Wang BJ, Mu YM.Gene Expression Profile of Persistent Postoperative Hypertension Patients with Aldosterone‑producing Adenomas. Chinese Medical Journal,June 20, 2015, Volume 128 ,Issue 12. (通讯作者,IF=1.053)
88. Tian Y, Chen K, Xie Z, Fang Y, Wang H, Nie Y, Hu D, Mu Y.The association between serum uric acid levels, metabolic
综合征 and cardiovascular disease in middle aged and elderly
汉语词类: results from the DYSlipidemia International Study. BMC Cardiovascular Disorders. 12/2015; 15(1):66. (通讯作者,IF=1.878)
89. Sun X, Hao H, Han W, Mu Y.Effects of conditioned media for rat bone marrow-derived mesenchymal stem cells on palmitic acid-induced
胰岛素 resistance in HepG2 cells. Zhonghua Nei Ke Za Zhi. 2015 May;54(5):439-44. Chinese. (通讯作者)
90. Yang L, Wang A, Zhang Y, Mu Y.12 cases of primary thyroid lymphoma in China. Journal of endocrinological investigation 03/2015; 38(7). (通讯作者)
91. Wang S, Yang L, Li J, Mu Y.Concurrent insulinoma with mosaic Turner
综合征: A case report. Exp Ther Med. 2015 Mar;9(3):801-804. Epub 2015 Jan 5.(通讯作者)
92. Zhang M, Tong G, Liu Y, Mu Y, Weng J, Xue Y, Luo Z, Xue Y, Shi L, Wu X, Sun S, Zhu Y, Cao Y, Zhang J, Huang H, Niu B, Li H, Guo Q, Gao Y, Li Z, Ning G, Zhu D, Li X; HHIS Study Group.Sequential Versus Continual Purified Urinary FSH/hCG in Men With Idiopathic Hypogonadotropic Hypogonadism.J Clin Endocrinol Metab. 2015 Jun;100(6):2449-55.(第四作者)
93. Zhan XR, Mu YM, Pan CY, Xiao YJ, Lu ZQ, Liu FH, Li XY, Yu JJ. Life and
死亡 of human vascular endothelial cells by stimulation with free fatty acids through death receptors. Horm Metab Res. 2015 Feb;47(2):107-13. (第二作者)
94. Gu WJ, Zhang Q, Wang YQ, Yang GQ, Hong TP, Zhu DL, Yang JK, Ning G, Jin N, Chen K, Zang L, Wang AP, Du J, Wang XL, Yang LJ, Ba JM, Lv ZH, Dou JT, Mu YM.Mutation analyses in pedigrees and sporadic cases of ethnic Han Chinese Kallmann
综合征 patients. Experimental Biology and Medicine 06/2015(通讯作者)
95. Gu WJ, Yan HX, Luo YK, Wang FL, Yang GQ, Guo QH, Jin N, Zang L, Chen K, Du J, Wang XL, Yang LJ, Ba JM, Dou JT, Mu YM, Pan CY, Lv ZH. Characterization of papillary thyroid microcarcinomas using sonographic features in malignant papillary thyroid cancer: a retrospective analysis. Medicine (Baltimore). 2015 May;94(21):e841. doi: 10.1097/MD.0000000000000841.
96. Zheng Y, Wang A, Pan C, Lu J, Dou J, Lu Z, Ba J, Wang B, Mu Y.Impact of night sleep duration on glycemic and
三酸甘油脂 levels in Chinese with different glycemic status. J
糖尿病 2015 Jan;7(1):24-30. (通讯作者)
著作译作
主编《解放军总医院临床临床内分泌代谢病学》《解放军总医院内分泌代谢病临床经典病例》《内分泌代谢病临床经典病例-下丘脑垂体专辑》《实用临床内分泌诊疗手册》《胰岛素泵规范治疗教程》《临床药物治疗学内分泌代谢疾病》《高尿酸血症和痛风实用诊疗手册》《国内外糖尿病指南与专家共识解读荟萃》《实时动态胰岛素泵系统(3C疗法)病例集》《内分泌代谢病临床用药及点评》。
社会任职
《Chronic Diseases and Translational Medicine》《
中华内分泌代谢杂志》《实用内科杂志》《
解放军医学杂志》和《中国医学前沿杂志》副主编;《药品评价杂志》主编。
中华医学会内分泌学分会第十届委员会主任委员、解放军医学会内分泌专业委员会主任委员、
中国医师协会内分泌代谢分会副会长、北京市医学会内分泌学分会主任委员。
社会活动
近15年来从事
干细胞治疗
糖尿病及其并发症的基础和临床研究。并进行了大量的糖尿病及内分泌慢性疾病的科普宣传,分别在
中央电视台综合频道、CCTV2、CCTV4和
中央电视台科教频道,以及
北京卫视和江苏卫视做科普讲座200余场,在
新华网、
百度集团、
腾讯控股、
人民网股份有限公司以及
央视网等媒体做糖尿病等健康讲座50余次。
获得荣誉
2008年获得全军杰出青年基金。
2012年和2018年被中华医学会授予杰出贡献奖。
先后荣立三等功、解放军总医院优秀博士生导师、十佳教师和优秀党支部书记。
曾获全军
科学技术进步奖二等奖一项和
三等奖多项以及解放军总医院医疗成果二等奖5项。